Wednesday, April 15, 2015

The plan

Trial plan:

·         Using 10,000 mcg (microgram) biotin from Natrol via Amazon.com
See Which biotin
·         Taking biotin with Swiss chard (just a pinch) or peanuts sunflower seeds (just a few)
·         1 unit once per waking hour
o   Or 2 units per 2 hours if necessary, always with biotin containing food
·         1-2 units if I wake up in the middle of the night for anything
·         Target 15 – 20 units daily
·         Maintain this plan for at least 12 months
·         Keep a log of actuals – recognizing that this is a difficult plan to adhere to

Rationale:

·         Patent based on 100 mg – 600 mg daily was well tolerated, therefor 200 mg should be safe
o   Biotin is water soluble and doesn’t build up in the body – excess will be excreted
o   Results were seen in case studies as low as 100 mg daily, most patients were given 300 mg
o   150-200 at the suggested interval most likely as effective as 300 in 3 daily doses
·         Half-life of biotin is 2 hours – that is why the frequent distributed dosing schedule
·         Food containing biotin most likely also contain elements that aid in the body’s absorption of biotin
o   Peanuts, swiss chard, egg yolks (but egg yolks contain saturated fat which is contra-indicated for MS)
·         Patients took 2 – 12 months to see results.  Will commit to this study for 12 months
o   Patients had very advanced progressive MS and still saw improvements – very exciting research geared towards recovering lost function

Considerations:

·         All indications are that this is safe.  Still – we are talking about hundreds or thousands of times the daily recommendation for Biotin
·         I’ve estimated cost to be around $45 per month.
o   There is a cheaper but less convenient and safe way to do this
o   Bulk pharmaceutical grade biotin is available for $166 / kg which would last more than a year at this dosing plan
o   This is less safe and less accurate and only saves $384 over the course of a year.  I don’t recommend it.

3 comments:

  1. Baseline information:

    Dx in March 2003

    On copaxone uneventfully from 2003 until around 2009.

    Noticed some deterioration in balance from 2009 - 2011.

    Began Swank diet in 2011. Balance and athleticism had already suffered at this point.

    In 2013 (July) I switched from Copaxone to Tecfidera.

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  2. Baseline continued:

    In July 2014 began NUCCA chiropractic care

    Missed the litany of supplements- continuing to this day with cod liver oil, vitamin d, circummin, Padma, b12, evening primrose oil.

    In December of 2014 switched back to copaxone from Tecfidera in response to lymphopenia.

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