Tuesday, June 30, 2015
Sunday, June 28, 2015
Saturday, June 27, 2015
Thursday, June 25, 2015
Tuesday, June 23, 2015
Monday, June 22, 2015
Sunday, June 21, 2015
Saturday, June 20, 2015
Thursday, June 18, 2015
Wednesday, June 17, 2015
Tuesday, June 16, 2015
Monday, June 15, 2015
Slight change to trial plan
given that adequate rest is an important element of the Swank diet and lifestyle, I sm going to try to cut down on dose logging at night.
Plan is to take enough at bedtime to get to 200 mg for day and take 20 - 30 mg at wake up with few - no midnight doses.
Plan is to take enough at bedtime to get to 200 mg for day and take 20 - 30 mg at wake up with few - no midnight doses.
Sunday, June 14, 2015
Saturday, June 13, 2015
Friday, June 12, 2015
Thursday, June 11, 2015
Wednesday, June 10, 2015
Monday, June 8, 2015
Sunday, June 7, 2015
Saturday, June 6, 2015
Thursday, June 4, 2015
The Plan (reposted at day 52)
Trial plan:
· Using 10,000 mcg (microgram) biotin from Natrol via Amazon.com
See Which biotin - now using Natures bounty exclusively. It is d-biotin, calcium free, $9 per 6 day supply (120 x 10 mg is 6 days per my protocol).
See Which biotin - now using Natures bounty exclusively. It is d-biotin, calcium free, $9 per 6 day supply (120 x 10 mg is 6 days per my protocol).
· 1 unit once per waking hour
o Or 2 units per 2 hours if necessary, always with biotin containing food
· 1-2 units if I wake up in the middle of the night for anything
· Target 15 – 20 units daily (19 - 21 units daily so far)
· Maintain this plan for at least 12 months
· Keep a log of actuals – recognizing that this is a difficult plan to adhere to
Rationale:
· Patent based on 100 mg – 600 mg daily was well tolerated, therefor 200 mg should be safe
o Biotin is water soluble and doesn’t build up in the body – excess will be excreted
o Results were seen in case studies as low as 100 mg daily, most patients were given 300 mg
o 150-200 at the suggested interval most likely as effective as 300 in 3 daily doses
· Half-life of biotin is 2 hours – that is why the frequent distributed dosing schedule
· Food containing biotin most likely also contain elements that aid in the body’s absorption of biotin
o Peanuts, swiss chard, egg yolks (but egg yolks contain saturated fat which is contra-indicated for MS)
· Patients took 2 – 12 months to see results. Will commit to this study for 12 months
o Patients had very advanced progressive MS and still saw improvements – very exciting research geared towards recovering lost function
Considerations:
· All indications are that this is safe. Still – we are talking about hundreds or thousands of times the daily recommendation for Biotin
· I’ve estimated cost to be around $45 per month.
o There is a cheaper but less convenient and safe way to do this
o Bulk pharmaceutical grade biotin is available for $166 / kg which would last more than a year at this dosing plan
o This is less safe and less accurate and only saves $384 over the course of a year. I don’t recommend it.
Wednesday, June 3, 2015
Tuesday, June 2, 2015
Day 49
210 mg yesterday.
Yesterday was very uneven with lots of missed doses and double doses. I was extremely busy from early AM to late PM.
Part of the reason for keeping this log is recognition that 10 mg 20 x per day is an ambitious plan. I want to be able to look back and see the "actual" - not just the idealistic version of what I think I did.
Yesterday was very uneven with lots of missed doses and double doses. I was extremely busy from early AM to late PM.
Part of the reason for keeping this log is recognition that 10 mg 20 x per day is an ambitious plan. I want to be able to look back and see the "actual" - not just the idealistic version of what I think I did.
Monday, June 1, 2015
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