Tuesday, June 30, 2015

Sunday, June 28, 2015

Saturday, June 27, 2015

Thursday, June 25, 2015

Tuesday, June 23, 2015

Monday, June 22, 2015

Sunday, June 21, 2015

Saturday, June 20, 2015

Thursday, June 18, 2015

Wednesday, June 17, 2015

Tuesday, June 16, 2015

Day 63

210 mg yesterday

Paper and pen logged night time doses:

2:00
2:00
4:00
4:00
6:25
6:25

Monday, June 15, 2015

Slight change to trial plan

given that adequate rest is an important element of the Swank diet and lifestyle, I sm going to try to cut down on dose logging at night.

Plan is to take enough at bedtime to get to 200 mg for day and take 20 - 30 mg at wake up with few - no midnight doses.

Sunday, June 14, 2015

Saturday, June 13, 2015

Day 60

Day 60 - any day now on more concrete results!

210 mg yesterday.

Friday, June 12, 2015

Thursday, June 11, 2015

Wednesday, June 10, 2015

Monday, June 8, 2015

Sunday, June 7, 2015

Saturday, June 6, 2015

Thursday, June 4, 2015

The Plan (reposted at day 52)

Trial plan:

·         Using 10,000 mcg (microgram) biotin from Natrol via Amazon.com
See Which biotin - now using Natures bounty exclusively.  It is d-biotin, calcium free, $9 per 6 day supply (120 x 10 mg is 6 days per my protocol).
·         Taking biotin with Swiss chard (just a pinch) or peanuts sunflower seeds (just a few)
·         1 unit once per waking hour
o   Or 2 units per 2 hours if necessary, always with biotin containing food
·         1-2 units if I wake up in the middle of the night for anything
·         Target 15 – 20 units daily (19 - 21 units daily so far)
·         Maintain this plan for at least 12 months
·         Keep a log of actuals – recognizing that this is a difficult plan to adhere to

Rationale:

·         Patent based on 100 mg – 600 mg daily was well tolerated, therefor 200 mg should be safe
o   Biotin is water soluble and doesn’t build up in the body – excess will be excreted
o   Results were seen in case studies as low as 100 mg daily, most patients were given 300 mg
o   150-200 at the suggested interval most likely as effective as 300 in 3 daily doses
·         Half-life of biotin is 2 hours – that is why the frequent distributed dosing schedule
·         Food containing biotin most likely also contain elements that aid in the body’s absorption of biotin
o   Peanuts, swiss chard, egg yolks (but egg yolks contain saturated fat which is contra-indicated for MS)
·         Patients took 2 – 12 months to see results.  Will commit to this study for 12 months
o   Patients had very advanced progressive MS and still saw improvements – very exciting research geared towards recovering lost function

Considerations:

·         All indications are that this is safe.  Still – we are talking about hundreds or thousands of times the daily recommendation for Biotin
·         I’ve estimated cost to be around $45 per month.
o   There is a cheaper but less convenient and safe way to do this
o   Bulk pharmaceutical grade biotin is available for $166 / kg which would last more than a year at this dosing plan


o   This is less safe and less accurate and only saves $384 over the course of a year.  I don’t recommend it.

Wednesday, June 3, 2015

Day 50

210 mg yesterday

Late start today

Tuesday, June 2, 2015

Day 49

210 mg yesterday.

Yesterday was very uneven with lots of missed doses and double doses.  I was extremely busy from early AM to late PM.

Part of the reason for keeping this log is recognition that 10 mg 20 x per day is an ambitious plan.  I want to be able to look back and see the "actual" - not just the idealistic version of what I think I did.

Monday, June 1, 2015